What’s the difference between Skin boosters, Profhilo and Polynucleotides?

You’ve probably encountered terms such as Profhilo, skin boosters, and polynucleotides. But do you know what they are and how they vary? This short guide delves into these treatments, comparing their uses, advantages, and scientific principles. This will assist in selecting the ideal one for your skin.

1. Profhilo: Bioremodeling for Overall Skin Quality

Profhilo is a unique injectable with the highest concentration of hyaluronic acid (HA). Unlike a dermal filler, Profhilo doesn’t add volume. Instead, Profhilo stimulates collagen and elastin production, your skin’s natural support. It is injected using the 5-point BAP technique, which ensures a uniform distribution, making it particularly effective for improving skin tone, texture, and elasticity in areas like the face, neck, and hands.

Benefits of Profhilo

  • Improves overall skin quality, texture, and elasticity.
  • Promotes hydration and a subtle lifting effect.
  • Delivers natural-looking rejuvenation.


  • For most people, Profhilo requires two sessions spaced four weeks apart.
  • Results can last up to 6 months.
Profhilo in a box

2. Skin Boosters: Targeted Hydration and Rejuvenation

Skin boosters are a category of injectables containing hyaluronic acid (HA) in varying concentrations. They are injected superficially into the skin to address specific concerns.

Benefits of Skin Boosters:

  • Deep hydration for a plump and dewy complexion.
  • Reduction of fine lines and wrinkles.
  • Improvement in skin texture and tone.


  • The number of sessions and type of skin booster used depend on your goals and needs.
  • Results typically last 3-6 months.
two sysringes of sosum soft skin booster

3. Polynucleotides: Cellular Repair and Anti-Ageing Power

Polynucleotides are injectable biomaterials derived from salmon DNA. They stimulate cellular repair processes and collagen production within the skin.

Benefits of Polynucleotides:

  • Promotes skin regeneration and rejuvenation.
  • Improves skin texture and elasticity.
  • Polynucleotides offer long-lasting anti-ageing effects.


  • May require a series of treatments spaced a few weeks apart.
  • Results can last up to a year.
phil art injectable polynucleotide skin booster 2

Polynucleotides vs Skin Boosters vs Profhilo: Choosing the Right Treatment:

The best choice for you depends on your specific skin concerns and the desired outcome:

  • For overall skin quality improvement and a natural lift, Profhilo could be the ideal option.
  • For targeted hydration, wrinkle reduction, and a dewy glow, Skin boosters are for you.
  • For advanced rejuvenation, cellular repair, and long-lasting results, Consider polynucleotides.

Remember: Consistent skincare practices are crucial to complement and enhance the effects of these injectable treatments.


So, there you have it! Profhilo, skin boosters, and polynucleotides offer distinct approaches to achieving radiant and youthful-looking skin. Understanding their differences should now allow you to make the right choices for your skin!

Andy Taylor

I am a Consultant working in the NHS specialising in non-surgical aesthetic treatments.